After first listing him as questionable on Friday’s injury report, Seattle downgraded the punishing running back to out.
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The team said Lynch did not travel with the team to Minnesota after he “felt like he couldn’t play” following his workout Friday.
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Lynch has missed the Seahawks’ past seven games after undergoing surgery to repair a sports hernia.
The combination of Christine Michael, Bryce Brown and Fred Jackson will continue to carry the rushing load for Seattle as it aims for a third consecutive trip to the Super Bowl.