Spieth and Rory McIlroy are behind at 8-to-1, with Bubba Watson, a two-time winner at Augusta, at 10-to-1.
MORE: Hole-by-hole look at Augusta National
Masters betting props
What will the 36-hole cut be? Over/under 147.5
Lowest round by any golfer Over/under 65.5 (under -130)
Will there be a hole in one? Yes -110 No -110
Will there be a playoff? Yes +290 No -350
Masters betting matchups
Jason Day -115 Rory McIlroy -105
Jason Day -135 Jordan Spieth +115
Rory McIlroy -130 Jordan Spieth +110
Jason Day -130 Bubba Watson +110
Jason Day -135 Adam Scott +115
Rory McIlroy -125 Bubba Watson +105
Jordan Spieth -120 Bubba Watson +100
Dustin Johnson +105 Bubba Watson -125
Adam Scott -130 Rickie Fowler +110
Adam Scott -120 Dustin Johnson +100
Adam Scott -140 Phil Mickelson +120
Rickie Fowler -115 Dustin Johnson -105
Rickie Fowler -130 Phil Mickelson +110
Rickie Fowler -115 Justin Rose -105
Dustin Johnson -130 Phil Mickelson +110
Henrik Stenson -110 Justin Rose -110
Henrik Stenson -150 Charl Schwartzel +130
Louis Oosthuiezen -110 Charl Schwartzel -110
Henrik Stenson -135 Louis Oosthuizen +115
Justin Rose -150 Charl Schwartzel +130
Hideki Matsuyama -135 Patrick Reed +115
Hideki Matsuyama =145 Zach Johnson +125
Patrick Reed -110 Zach Johnson -110
Zach Johnson -125 Brandt Snedeker +105
Brandt Snedeker +105 Sergio Garcia -125
Brandt Snedeker -110 Danny Willett -110
Sergio Garcia -110 Matt Kuchar -110
Sergio Garcia -125 Danny Willett +125
Marc Leishman +105 Matt Kuchar -125
Marc Leishman +105 Paul Casey -125
Matt Kuchar -110 Paul Casey -110
Brooks Koepka -120 Branden Grace +100
Brooks Koepka -120 Jimmy Walker +100
Branden Grace -105 Jimmy Walker -115
Jason Dufner +110 Justin Thomas -130
Paul Casey -120 Danny Willett +100