Read on to find out more about how medical marijuana can be used for MS, as well as potential side effects, risks, and benefits.
Talk with your healthcare provider before using medical marijuana.
Why Cannabis Might Help With MS
Cannabis, or marijuana, has more than 80 chemical compounds called cannabinoids in it. The most commonly known ones are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is what gives the “high” from marijuana. It attaches to cannabinoid receptors in the brain, producing feelings of happiness, relaxation, altered sensory perception, and increased appetite.
The American Academy of Neurology published evidence-based guidelines back in 2014 about cannabinoids for MS-related symptoms. They found that people living with MS found relief for spasticity, pain, and urinary frequency. That being said, studies are still being done to assess this, with varying results.
Benefits of Marijuana for MS
A 2021 study found that people reporting the most benefit from marijuana, or improvements in two or more symptoms, were those with a milder form of MS and less disability. Those who needed help with mobility found less of a benefit from cannabis than those who did not.
Benefits of using marijuana for MS can include improvements in:
Mood Pain Muscle cramps and spasms Insomnia
Participants in one study (a little less than half) reported decreasing or stopping certain medications when they used marijuana. These medications included opioid and non-opioid pain medications, benzodiazepines, and muscle relaxers.
Side Effects of Cannabis
While many people use cannabis for both recreational and medicinal purposes, it is not free of risk. Potential side effects of cannabis include:
Cognitive impairmentAnxiety and/or paranoiaDry eyesNausea and/or vomitingSedationIncreased appetiteHeadacheImpaired balance/coordinationIncreased heart ratePossible risks to lung health (if smoked)
How to Use Cannabis for MS
Medical marijuana is different from recreational marijuana. The Food and Drug Administration (FDA) has approved one cannabis-derived drug product, Epidiolex (cannabidiol), and three synthetic cannabis-related drugs, which are:
Marinol (dronabinol): Used to treat nausea and vomiting due to chemotherapy Syndros (liquid dronabinol): Used to treat nausea and vomiting due to chemotherapy, as well as anorexia in adults with AIDS who have lost weight Cesamet (nabilone): Used to treat nausea and vomiting due to chemotherapy in those who have not been helped by other therapies
These are prescription-only drugs and are not available over the counter (without a prescription).
Dosage
The dosage for medical cannabis can vary, depending on the person and their symptoms, as well as their overall health. For chronic pain, a typical starting dose of a CBD-predominant drug is 5 milligrams (mg) CBD twice daily, and the provider can increase the CBD-predominant drug by 10 mg every two to three days, up to 40 mg per day. They can then add THC to the dosage if need be, starting at 2.5 mg, and increasing by 2.5 mg every two to seven days for a maximum of 40 mg per day of THC.
Who Shouldn’t Use It
Medical cannabis may not be for everyone. It can increase the risk of developing psychosis in those who have experienced such symptoms before and those with a family history of schizophrenia.
It may also worsen cognitive symptoms for some people with MS, like working memory, executive functioning (a set of mental processes that help a person plan, focus on, and execute goals), and information processing speed. It can also increase the risk for cardiovascular diseases, like high blood pressure, heart failure, and stroke.
If you’re interested in medical cannabis, talk with your healthcare provider. Tell them about your medical and family history, and any concerns you might have. Together, you can discuss whether it would be safe for you to use.
Summary
Medical marijuana may be an option for some people living with MS. Depending on what state you live in and your specific medical situation, medical marijuana may be a beneficial tool to add to your treatment regimen. It has been shown to have positive effects on symptoms like pain and spasticity, and has allowed some people to reduce their consumption of medications like opioids and benzodiazepines.
A Word From Verywell
Medical marijuana may not be the best option for some people, and you and your healthcare provider can discuss the risks and benefits. It’s important to remember that medical marijuana is not the same as recreational marijuana, and they should not be used interchangeably.
If you do live in a state where cannabis is legal for certain medical conditions and your healthcare provider deems it medically necessary for your MS, they can prescribe it for you.
It is not covered by insurance, so you will have to pay for it out of pocket.
